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教师风采

曾昕 副教授

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职称:副教授

学历/学位:研究生/博士

毕业院校/专业:江南大学/发酵工程

电子邮箱:xzenghsd@163.com 

 

简介:安徽省优青,日照市创新领军人才,淮北师范大学相山学者,安徽省科技副总,淮北市双链融合专员长期从事发酵工程、微生物源生物防腐剂的发酵合成、生防产品高效生物制造等领域研究,承担《生物工程设备与设计》、《现代工业发酵调控学》、《微生物工程实验》、《生物工艺学实验》、《生物工程综合实验》等课程的教学。发表论文50余篇,申请国家发明专利10余项,其中已授权7项,3项完成成果转化,主持包括国家自然科学面上项目、国家自然科学青年基金项目、安徽省自然科学基金优青项目等在内的项目13项,目前担任国家、省市级科技项目评审专家及多家SCI期刊审稿专家。

 

学习工作经历:

2020-至今 淮北师范大学,副教授、硕士生导师

2016-2020 淮北师范大学,讲师

2010-2016 江南大学,发酵工程,工学博士(硕博连读)

 

主要成果:

1、论文发表情况(第一或通讯作者):

(1) Multilevel systemic engineering of Bacillus licheniformis for efficient production of acetoin from lignocellulosic hydrolysates. International Journal of Biological Macromolecules, 2024, 279, 1, 135142.

(2) Transcriptional analysis revealing the improvement of ε-poly-L-lysine production from intracellular ROS elevation after Botrytis cinerea induction. Journal of Fungi, 2024, 10, 324.

(3) Polysaccharides of Aspergillus cristatus isolated from Fu-brick tea attenuate obesity by regulating gut microbiota and gut microbiota-related metabolites, Food Science and Human Wellness, 2023, 13(3): 1513-1530.

(4) Improvement of ε-poly-l-lysine production by co-culture fermentation strategy, Fermentation-Basel, 2023, 9(7), 626. 

(5) Physiological analysis of the improved ε-polylysine production induced by reactive oxygen species, Applied Microbiology and Biotechnology, 2023, 107, 881–896.

(6) Transcriptome and metabolome analysis revealing the improved epsilon-poly-L-lysine production induced by a microbial call from Botrytis cinerea, Applied and Environmental Microbiology, 2022, 88 (20), e00952-22.

(7) Waste cooking oil: new efficient carbon source for natamycin production by Streptomyces gilvosporeus Z8, Process Biochemistry, 2022, 118: 294–306.

(8) Improvement of natamycin production by controlling the morphology of Streptomyces gilvosporeus Z8 with microparticle talc in seed preculture, Journal of Chemical Technology and Biotechnology, 2021, 96: 1533–1542.

(9) Tea consumption and colorectal cancer risk: a meta-analysis of prospective cohort studies, European Journal of Nutrition, 2020, 59:3603-3615.

(10) Continuous natamycin production by using immobilized Streptomyces gilvosporeus Z8 via repeated batch culture, Journal of Chemical Technology and Biotechnology, 2019, 95:73-77.

(11) Transcriptional study of the enhanced ε-poly-L-lysine productivity in culture using glucose and glycerol as a mixed carbon source, Bioprocess and Biosystems Engineering, 2019, 42, 555-566.

(12) Production of natamycin by Streptomyces gilvosporeus Z28 through solid-state fermentation using agro-industrial residues, Bioresource Technology, 2019, 273: 377-385.

(13) Insights into the simultaneous utilization of glucose and glycerol by Streptomyces albulus M-Z18 for high ε-poly-L-lysine productivity, Bioprocess and Biosystems Engineering, 2017, 40: 1775-1785.

(14) Improved ε-poly-L-lysine productivity partly resulting from rapid cell growth in culture using a glucose-glycerol mixed carbon source, Engineering in Life Sciences, 2016, 16: 443-452.

(15) Continuously high reactive oxygen species generation decreased the specific ε-poly-L-lysine formation rate in fed-batch fermentation using glucose and glycerol as a mixed carbon source, Process Biochemistry, 2015, 50: 1993-2003.

(16) Insights into the role of glucose and glycerol as a mixed carbon source in the improvement of ε-poly-L-lysine productivity, Applied Biochemistry and Biotechnology, 2014, 173:2211-2224.

 

2、授权发明专利情况(第一发明人):

(1)一种基于发酵废菌渣交互回用的ε-聚赖氨酸-纳他霉素协同生产方法;专利号:ZL202110618978.4

(2)一种基于柠檬酸发酵废弃物的聚赖氨酸生物合成方法;专利号:ZL202110618983.5

(3)一种利用霉变水果为碳源发酵合成ε-聚赖氨酸的方法,专利号:ZL202110618602.3

(4)一种添加微生物诱导子的ε-聚赖氨酸生物合成方法,专利号:ZL202110618607.6

(5)一种基于外源饱和脂肪酸添加的纳他霉素发酵工艺,专利号:ZL201910369887.4 (已转化)

(6)一种基于细胞固定化技术的纳他霉素发酵工艺,专利号:ZL201910369890.6 (已转化)

(7)一种利用工农业副产物固态发酵合成那他霉素的方法,专利号:ZL201811230431.1 (已转化)

 

3正在实审发明专利(第一发明人):

(1)一种基于链霉菌混合发酵合成纳他霉素的方法;专利号:202211398321.2;

(2)一种链霉菌-霉菌混合发酵合成ε-聚赖氨酸的工艺;专利号:202211398323.1;

(3)一种半固态发酵合成ε-聚赖氨酸的方法;专利号:202211443897.6;

 

4、主持项目情况(省级以上)

(1)安徽省科技厅优秀青年项目,2408085Y019,2024-2027

(2)安徽省教育厅优秀青年教师培育重点项目,YQZD2023038,2024-2026

(3)国家自然科学基金面上项目32372308,2024-2027

(4)安徽省高校自然科学基金重点项目,2023AH050327,2024-2025

(5)国家自然科学基金青年基金项目,31901672,2020-2022

(6)安徽省自然科学基金面上项目,1908085MC57,2019-2022

(7)安徽省高校自然科学基金重点项目,KJ2020A0042,2020-2022

 

5、获奖情况:

(1)淮北师范大学青年相山学者

(2)2022-2023年度师德标兵

(3)2018-2019年度优秀教师

(4)2020年院级优秀共产党员

 

6、指导学生项目及获奖情况:

(1)安徽省大学生创新创业计划项目(2018、2019、2020、2021、2022年)

(2)2023年国家级大学生创新创业计划项目

(3)2024年中国国际大学生创新大赛安徽赛区金奖

(4)第九届安徽省“互联网+”大学生创新创业大赛银奖

(5)第十届“挑战杯”安徽省大学生课外学术科技作品竞赛三等奖

(6)第八届全国大学生生命科学竞赛(创新创业类)三等奖2项

(7)2023年安徽省大学生生态环境创新创业大赛三等奖

(8)淮北师范大学第九届“学术新锐”研究生论坛二等奖

(9)第二届创业安徽大赛淮北赛区选拔赛优秀奖

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